Web24 lug 2014 · The DrugMatrix contains 5,587 gene expression profiles from male rat primary tissues (liver, kidney, heart and thigh muscle) and cultured rat hepatocytes, corresponding to treatments with 376 chemicals, and including 994 control samples from rats kept in matched conditions. Web17 ago 2024 · The data for chloroquine derivative medication were extracted from the GSE30351 dataset. The expression of ACE2 and TMPRSS2 was also analyzed in medication treated primary rat hepatocytes (Supplementary Fig. 1). The rat in-invitro treatments were obtained from DrugMatrix toxicogenomic database (GSE57805).
An Overview of National Toxicology Program’s Toxicogenomic
WebDrugMatrix, collected from rats exposed to a chemical for 5 days. A global in vitro-to-in vivo comparative analysis based on pathway-level responses resulted in an overall average percent ... Web31 ago 2024 · DrugMatrix is a comprehensive rat toxicogenomics database and analysis tool developed to facilitate the integration of toxicogenomics into hazard assessment. … lampada biassono
Drug vector representation: a tool for drug similarity analysis
Web24 giu 2024 · May 2013 - Present10 years. Palo Alto, CA. As the founder and managing director of enlightenbio leading business strategies, championing market vision, and managing all client efforts and day-to ... Web1 lug 2024 · Schematic diagram for DrugMatrix data analysis. By latent semantic analysis (LSA), treatment data were reduced to 100-dimensional vectors. Then, cosine similarity … [email protected]. Description: DrugMatrix is the scientific communities' largest molecular toxicology reference database and informatics system. DrugMatrix is populated with the comprehensive results of thousands of highly controlled and standardized toxicological experiments in which rats or primary rat hepatocytes were systematically ... jessamine carolina